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NGS: A New Technology for Improving Food Safety

4/21/2019 by Quick Biology Inc.

Eating habits is the critical aspect of our Healthy lifestyle.  Balanced food choice (with different nutrients) over time will make good health of us.  Recently, due to environmental pollution across the world, food safety is being increasingly scrutinized and questioned by the public.  Outbreaks and diseases caused by foodborne pathogens place a heavy burden on health (Table 1). Traditional methods for the detection of foodborne microbes are PCR (polymerase chain reaction) or culture-based technologies to measure microbial composition, the big drawback of these is that microbial communities evolve fast, it only detects limited known microbe, many microbes are non-culturable.  NGS (Next Generation Sequencing)-based platforms allow more complete visibility to food microbe system, enabling more informed risk management decisions, thanks to NGS, our food industry is beginning to transition into an era of big data (Figure 1).   

Table 1: Contribution of Viruses to the global burden of foodborne disease (source from [1])

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Figure 1: Summary of potential NGS use by the food industry (source from [2])

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See the articles:

1. Bosch, A., Gkogka, E., Le Guyader, F. S., Loisy-Hamon, F., Lee, A., van Lieshout, L., … Phister, T. (2018). Foodborne viruses: Detection, risk assessment, and control options in food processing. International Journal of Food Microbiology, 285(May), 110–128. https://doi.org/10.1016/j.ijfoodmicro.2018.06.001

2.  Jagadeesan, B., Gerner-Smidt, P., Allard, M. W., Leuillet, S., Winkler, A., Xiao, Y., … Grant, K. (2019). The use of next generation sequencing for improving food safety: Translation into practice. Food Microbiology, 79(October 2018), 96–115. https://doi.org/10.1016/j.fm.2018.11.005